“What Exactly Causes Itching”: 25 Mysteries Of The Human Body

Some people are blessed with the ability to be so in touch with their bodies that they can sense when something is intrinsically wrong with them. These people usually have to insist that health professionals conduct the right tests to find the issue because outwardly they don’t display typical symptoms. But folks who do the tests at the right time can detect medical issues and cure them before they develop to a critical stage. Because we don’t all seem to have this ability, some may even consider it a superpower. But the reality is that despite the advances we have made in medical studies, we don’t know everything about the human body or what we are truly capable of without limitations. 

#1

Image source: beboleche, Andrej Lišakov/Unsplash (not the actual photo)

One of the few ABSOLUTES in medical science is that nobody born blind has ever developed schizophrenia.

#2

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Not a doctor but a speech pathologist – we still don’t fully understand what causes people to develop a stutter. We know there’s sometimes a genetic link and that some children do it as a developmental stage that they grow out of. It’s very difficult to treat.

#3

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I’m a derm. We don’t know what exactly causes itching, like the molecular pathways for it. That’s why it can be so hard to find a good treatment when a patient comes in for itchy skin.

#4

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How basically any of medical science works in relation to women and their bodies – almost all the data is based on men, and a lot of it almost exclusively.

#5

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What causes endometriosis and how do you treat it effectively. The leading theory is “retrograde menstruation,” which occurs in 80-90% of women. Ok….. so why do 80-90% of women not have endometriosis? There’s clearly something else going on that we don’t know.

Also, the only way to remove or get rid of endometriosis is through surgery. But there is a high rate of recurrence after surgery. Some women undergo multiple surgeries for it.

#6

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One of the frustrating, but not so secret things in medicine is that racial differences exist and they can’t be discussed in today’s climate.

There are differences in d**g efficacy, growth, disease susceptibility or immunity just about everything.

It’s preventing personalized treatments. AI can now pretty accurately guess someone’s race and s*x from a single view chest xray so things may change.

People always think of this as a negative but in reality it should be approached like family history being super relevant for cancer or heart disease surveillance.

#7

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The Gut Microbiome: While it’s well-known that the gut plays a huge role in digestion, researchers are discovering just how much our gut bacteria affect other parts of our health, like mood, immunity, and even brain function.

#8

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One I didn’t see mentioned: we apparently don’t know precisely *how* our bodies can distinguish gas from poop. We have some ideas, we know there are a ton of nerve endings in the area, but the precise mechanism of our bodies telling our brains “this is a fart, let loose” isn’t really understood.

What blows my mind is, it’s distinct enough that we even pass gas while asleep. That difference must be wired DEEP!

#9

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I’m an anesthesiologist. We still don’t really know why inhaled volatile anesthetics like sevoflurane, the principle anesthetic agent used to maintain general anesthesia, work. We kind of have an idea of maybe how it happens, but really we don’t know

It’s commonly said in my field that whoever figures this out will win the next Nobel prize in medicine

#10

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I had a lecturer at medical school say “half of medicine is made up, we just don’t know which half”.

#11

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It’s not cancer. It’s cancer(S) and every specialized and stem cell (undifferentiated pluripotent cell) is at risk of mutating into something that doesn’t stop multiplying.

The cancer of a specialized gland cell is called adenocarcinoma.

The cancer of a skin cell is called squamous cell carcinoma.

The cancer of a melanocyte is melanoma and so on.

So anytime someone says, “they’re hiding the cure for cancer” they are being magnificently ignorant.

-Pathologist.

#12

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OBGYN here: we still don’t know exactly what makes labor start. We know all about the mechanics and physiology, but we don’t know what makes the average uterus say it’s “go time.”.

#13

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Doctor here. Off the top of my head, here’s a few deceptively big ones:

1) We still aren’t exactly sure how anesthesia works. We just know it causes certain effects, and they are useful so we use it.

2) psychiatry is still shockingly infantile in our understanding of human disorders. It’s constantly in a state of flux, we don’t understand a lot about the meds we currently use, and the diagnostic criteria for disorders still changes as we realize “hey maybe all these behaviors aren’t the same source disorder”. It’s incredibly hard to diagnose when the criteria is largely based on self report and subjective observations.

3) To a lesser degree than #2, neurology is still learning a lot. It’s further because you can observe more objective findings in neuro than psych, but we still struggle a lot with how brains function.

4) Immunology. Don’t even ask me, because no one knows really.

5) yawns. Still guessing on why that happens too. There’s some theories, but that’s the best we got.

#14

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Not a doctor but I study cell and molecular biology. The immune system is wildly complex and right now feels as though we’re staring down into Mariana’s trench.

#15

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Allergies, spefically food allergies . And why do adults develop them after never reacting to them before?

#16

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Had a pathologist tell me that the interesting part of his job wasn’t finding out how someone died, it was seeing everything that can be wrong with someone, so many life threatening or life altering, horrible things that a person can have going on and still be alive.

Good friend died of pneumonia (he was too busy at work, couldn’t afford to take time off), he kept using OTC meds for the symptoms.

He died unattended, so the coroner had to get involved, they did an autopsy. His body had cancer in three different places, he never stopped.

Dude was old-time tough.

#17

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Apparently we know next to nothing about fibroids, which like 75% of women have at some point in their lives. That’s great, considering that the largest one removed was 100 lbs- so not exactly a minor issue.

There are theories about different hormones and what things put you at higher risk, but aside from having surgery to have your existing ones removed, there is basically no information on what you can to do prevent them from coming back.

#18

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Not a doctor, but the amount of ¯_(ツ)_/¯ I got from doctors when I asked questions during my treatment for breast cancer was astounding. That’s not to imply they were useless or didn’t know what they were doing, I just asked a lot of questions lol.

Me: Why do I need to take Claritin before chemo?
Nurse: It helps with bone pain.
Me: Oh, that’s interesting, why is that?
Nurse: Nobody knows!

Me: What’s the cording I’m experiencing in my arm following my mastectomy?
Physical Therapist: Nobody actually knows what it’s made of or where it comes from!

Me: Why am I suddenly unable to eat gluten following my cancer treatment?
Gastro Doc: Trauma, probably?

Having cancer really made it clear to me that so much of the human body is still a mystery!

#19

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The placenta is the only human organ grown for a specific purpose then discarded when it is no longer needed.

#20

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The biggest one I want solved

How we remember things, how does our memory work?

Some headway has been made at MIT but it hasn’t been completely c*****d yet.

#21

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Not MD but PhD, right now we are working on the connection between our intestinal microbiome and neuropsychiatric disease and brain aging. For instance, people with inflammatory bowel disease are more likely to develop dementia and experience co-morbid anxiety and depression, but we dont know why.

#22

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“Unexplained Infertility”

…is the actual name, of an actual diagnosis, given to my wife and I, because according to every test, based on what modern medical science knows about fertility, we’re fine. We *should* be able to conceive. “All the numbers are right.” We probably even would be able to conceive, either of us, with different partners. But no one knows why the two of us can’t, *together*. And it happens to far more couples than anyone talks about. But the only diagnosis we all get, is “unexplained infertility”.

#23

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Why our brain doesn’t use its stem cells it has to heal itself.

#24

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Rabies pathology

Alzheimer’s etiology

Encephalitis lethargica/chronic fatigue syndrome.

#25

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I’m a nurse, not a doctor, but in school I learned that when in vitro fertilization was being pioneered, scientists were unable to create an embryo from the combination of s***m and egg. It wasn’t until they added female secretions in that they were able to produce viable embryos, and they don’t know what role those secretions play in the process.

This was about 15 years ago, so if anyone has new information on the topic I’d love to hear it!